Why the study?
Does cardiopulmonary bypass perfusion pressure influence the incidence of acute renal failure in adult patients undergoing cardiac surgery?
Population
179 adult patients with normal preoperative renal function who had been subjected to cardiac surgery on…
Comparison
Mean perfusion pressure during CPB maintained at… vs Mean perfusion pressure during CPB maintained at…
Design
RCT, Randomized into three groups
Follow-up
Early postoperative period
Authors
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Perfusion pressure targets (55-75 mmHg) during CPB do not affect ARF; confirms age, valve surgery, and bypass duration as primary risks.
Does cardiopulmonary bypass perfusion pressure influence the incidence of acute renal failure in adult patients undergoing cardiac surgery?
Cardiopulmonary bypass perfusion pressure does not influence the development of postoperative acute renal failure, whereas patient age, valve surgery, and prolonged bypass times are significant risk factors.
Širvinskas et al. (2008) studied this question.
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