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August 13, 2026Indian Journal of Sexually Transmitted Diseases and AIDS

Epidemiology and genotype distribution of cervical high-risk human papillomavirus infection among women in Punjab, India: A large-scale retrospective analysis

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Implication

Retrospective analysis identifies HPV prevalence and genotype associations with cervical lesions in women, suggesting urgent vaccination needs.

Key Points

  • This study aims to determine the prevalence and genotype distribution of high-risk HPV among women in Punjab and its association with cervical lesions.
  • Conducted retrospective analysis of electronic health records for HPV testing between January 2023 and July 2025.
  • Tested cervical samples using real-time polymerase chain reaction assay.
  • Included women participating in screening camps and those attending oncology departments.
  • Overall HPV prevalence was 13.8% (544/3919), with HPV-16 (35.7%) and HPV-18 (14%) as the most common genotypes.
  • Single genotype infections were most frequent at 66.5%; multiple infections were significantly associated with higher CIN 2/3 lesions (OR = 2.8, P = 0.032).
  • HPV-66-positive women had lower odds of developing high-grade CIN, but the findings were statistically nonsignificant (OR = 0.47, P = 0.33).

Cite This Study

A 2026 study studied this question.

synapsesocial.com/papers/6a7d75e62b0e0cff3f63ed2ahttps://doi.org/10.4103/ijstd.ijstd_5_26
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Also Consider

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  1. 1Prevalence and genotype distribution of human papillomavirus infection among 66000 women from 2014 to 2023 in the plateau region of Southwest China2024 · 20 citations
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  3. 3IFN-γ Produced by Human Papilloma Virus-18 E6-Specific CD4+ T Cells Predicts the Clinical Outcome after Surgery in Patients with High-Grade Cervical Lesions2007 · 53 citations
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  5. 5Prevalence and genotypic distribution of high-risk human papillomavirus (HPV) among ever-married women in coastal regions of Bangladesh2024 · 13 citations