What does this research mean for the field?

High-risk HPV has a prevalence of 16.55% among adult women in Northeast India, with HPV-16 and HPV-18 being the most common genotypes, and HPV positivity is strongly associated with the severity of cervical cytological abnormalities and specific reproductive risk factors. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate the prevalence of high-risk human papillomavirus (hrHPV) genotypes and examine their association with cervical cytological abnormalities in adult women.

September 5, 2026South Asian Journal of CancerOpen Access

Distribution of high-risk human papillomavirus and its association with cervical cytological abnormalities in women from Northeast India

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To evaluate the prevalence of high-risk human papillomavirus (hrHPV) genotypes and examine their association with cervical cytological abnormalities in adult women.
Cross-sectional screening study conducted among 562 women aged 18 to 50+ years in Barak Valley, Northeast India.
Participants were screened for nine hrHPV genotypes alongside liquid-based cytology classified by the cervical intraepithelial neoplasia (CIN) system.
Overall hrHPV prevalence was 16.55%, led by HPV-16 (12.28%) and HPV-18, with abnormal cytology occurring in 10.1% of participants (CIN 1: 5.9%, CIN 2: 3.0%, CIN 3: 1.2%; p < 0.001 for lesion severity).
HPV positivity was significantly associated with a history of warts (OR = 13.8, 95% CI = 8.17–23.2), irregular menstruation (OR = 4.72, 95% CI = 2.94–7.56), high parity (OR = 3.7, 95% CI = 2.11–6.5), pregnancy failure (OR = 2.33, 95% CI = 1.34–4.06), and nulliparity (OR = 2.21, 95% CI = 1.27–3.85).

Authors

PDPritam DasIndian Institute of Technology Kharagpur GBGulrukh BegumGauhati University

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Implication

Cross-sectional study reveals high-risk human papillomavirus linked to cervical lesion severity in adult women, highlighting the need for screening and vaccination.

Cite This Study

Das et al. (2026) studied this question.

synapsesocial.com/papers/6a9bd4436b95aff0620ebd36 https://doi.org/10.25259/sajc_5_2026

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Implication

Cross-sectional study reveals high-risk human papillomavirus linked to cervical lesion severity in adult women, highlighting the need for screening and vaccination.

Distribution of high-risk human papillomavirus and its association with cervical cytological abnormalities in women from Northeast India

Key Points

Discussion

Implication

Cite This Study

Distribution of high-risk human papillomavirus and its association with cervical cytological abnormalities in women from Northeast India

Key Points

Discussion

Implication

Cite This Study

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