Why the study?
Heart failure remains a leading cause of morbidity and mortality worldwide, characterized by rising prevalence and substantial heterogeneity in pathophysiology and treatment response.
Population
Adults with chronic heart failure
Design
Narrative review
Key result
This narrative review outlines heart failure pathophysiology and underscores phenotype-based classification, particularly for HFpEF, as a framework for personalized therapy.
Loading...
Offers comprehensive HF pathophysiology synthesis; leaves open phenotype-specific therapy trials before practice change.
This review provides a comprehensive framework for understanding heart failure pathophysiology and highlights phenotype-based classification, particularly for HFpEF, to guide personalized therapy.
A 2026 study conducted a review in Heart failure. This narrative review outlines heart failure pathophysiology and underscores phenotype-based classification, particularly for HFpEF, as a framework for personalized therapy.