Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 13, 2026

Daily photoprotection mitigates seasonal skin changes and supports skin longevity: a one-year in vivo 3D multiphoton microscopy study.

View Full Paper
Ask AI
Bookmark
Share

Authors

EREdouard RaynaudBLBarbara LynchBNBlandine Ngo

Discussion

Loading...

Member takes

Overview

Randomized trial demonstrates that daily photoprotection prevents skin changes in middle-aged women, highlighting its importance for skin longevity.

Key Points

  • This study aims to examine the impact of daily photoprotection on seasonal skin changes using advanced imaging techniques.
  • One-year randomized double-blind trial with 59 women aged 55-65 applying either a photoprotection product or vehicle.
  • In vivo assessments conducted across four seasonal time points using multiphoton microscopy.
  • Measurements included melanin density, epidermal morphology, elastin and collagen densities, and a 3D SAAID aging index.
  • The vehicle group showed a significant increase in melanin density (p<0.05) and decreased 3D-SAAID aging index (p<0.01) between winter and summer.
  • No significant seasonal skin changes were observed in the photoprotected group.
  • Daily SPF/PPD application effectively mitigated subclinical skin changes due to UV exposure.

Cite This Study

Raynaud et al. (2026) studied this question.

synapsesocial.com/papers/6a7d76502b0e0cff3f63fa3ehttps://doi.org/10.1159/spp/aetag002
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The effect of a broad spectrum sunscreen with visible light coverage on facial photoaging: A pilot study2024
  2. 2Sunscreen application substantially mitigates molecular perturbations induced by repetitive UV exposure and maintains healthy skin2026 · 2 citations
  3. 3Photoaging versus Chronological Aging – A Histological Study on Human Female Skin2024 · 2 citations
  4. 4Epigenetics changes differentiate between endogenous ageing and photoageing in skin and can detect sun-protection factor cream effects in a 5-month interventional study2026
  5. 5Counteracting Skin Aging In Vitro by Phytochemicals2025 · 2 citations