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August 13, 2026Blood Coagulation & Fibrinolysis

Correlation of clinico-hematological and biochemical features with quality of life in hemophilia patients

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Authors

MAMay AlMosharyEBEbtisam BakhshNQNahid Abdulhamid Qushmaq

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Overview

Cross-sectional study evaluates factors affecting quality of life in hemophilia patients, indicating significant impacts from disease severity and bleeding episodes.

Key Points

  • This study aims to assess how clinical, hematological, and biochemical factors correlate with the quality of life in hemophilia patients.
  • Cross-sectional study among hemophilia patients attending Cluster 2 Hospitals, Jeddah, Saudi Arabia
  • Used the 36-Item Short Form Health Survey (SF-36) to assess quality of life
  • Analyzed data using Pearson's correlation, one-way ANOVA, and multivariable logistic regression
  • Patients with severe hemophilia had lower physical functioning (35.58 vs. 55.92; P = 0.039) and emotional well-being scores (48.59 vs. 61.32; P = 0.031) than those with mild disease
  • Recurrent joint bleeding (≥2 episodes within 6 months) was associated with a reduced quality of life (AOR = 5.2; P < 0.001)
  • Increasing age negatively correlated with quality of life (r = -0.48; P < 0.001)

Cite This Study

AlMoshary et al. (2026) studied this question.

synapsesocial.com/papers/6a7d76792b0e0cff3f63fceehttps://doi.org/10.1097/mbc.0000000000001454
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Evaluation of Quality of Life in Children with Hemophilia2026
  2. 2Quality-of-Life Assessment and Pharmacokinetic Study in Hemophilia A Patients Undergoing Prophylactic Treatment2025 · 5 citations
  3. 3A Retrospective Observational Study of Quality of Life in a Northern Greece Population of People with Haemophilia2024 · 5 citations
  4. 4Quality of Life in People With Haemophilia: Results in the Framework of a Nationwide Registry in Colombia2026
  5. 5Exploring the relationship between condition severity and health-related quality of life in people with haemophilia A across Europe: a multivariable analysis of data from the CHESS II study2024 · 5 citations