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This review aims to explore the formulation strategies and advantages of Amphotericin B-loaded cubosomes in enhancing antifungal treatments.

August 13, 2026Open Access

Formulation and Evaluation of Amphotericin B-Loaded Cubosomes: A Comprehensive Review

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Review Evaluates Amphotericin B-loaded cubosomes for antifungal delivery, highlighting efficacy and safety implications.

This review aims to explore the formulation strategies and advantages of Amphotericin B-loaded cubosomes in enhancing antifungal treatments.
Summarizes formulation strategies and preparation methods for cubosomes
Describes characterization techniques and recent advances in cubosomal systems
Discusses challenges and future perspectives for targeted antifungal therapies
Amphotericin B-loaded cubosomes exhibit enhanced solubility and sustained drug release
Demonstrated improved antifungal activity and reduced toxicity compared to conventional formulations
Highlighted superior pharmacokinetic performance leading to better therapeutic outcomes

B. Premkumar*, D. Dhachinamoorthi, P. R. Roshan Khumaar (2026) studied this question.

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