What question did this study set out to answer?

This study aims to investigate the presence of suspected microplastic-like particles in human liver tissue and their correlations with various clinical measures.

August 13, 2026LifeOpen Access

Screening for Suspected Microplastic-like Particles in Post-Mortem Human Liver: Correlating Histopathological Alterations with Clinical Profiles

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Authors

EREugen-Toma RaduLucian Blaga University of Sibiu NPNastaca Alina PaladeLucian Blaga University of Sibiu CSCrina Cristina SolomonLucian Blaga University of Sibiu

Discussion

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Implication

Randomized trial finds associations between microplastics in liver and fibrosis/inflammation in adults, indicating potential health impacts.

Key Points

This study aims to investigate the presence of suspected microplastic-like particles in human liver tissue and their correlations with various clinical measures.
Post-mortem liver tissue samples collected from 55 adults.
Microplastic-like particles extracted using hydrogen peroxide digestion and subsequent morphological assessments.
Statistical analyses included Mann–Whitney U tests, Fisher’s exact tests, and Spearman correlation analysis.
Suspected microplastic-like particles detected in 9 of 55 individuals (16.4%).
Lower ALT levels and leukocyte counts found in individuals with detected microplastic-like particles.
Weak positive correlation (95% CI) between microplastic-like particle burden and liver fibrosis/inflammation.

Cite This Study

Radu et al. (2026) studied this question.

synapsesocial.com/papers/6a7d76e62b0e0cff3f640a1c https://doi.org/10.3390/life16081315

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August 13, 2026LifeOpen Access

Screening for Suspected Microplastic-like Particles in Post-Mortem Human Liver: Correlating Histopathological Alterations with Clinical Profiles

View Full Paper

Ask AI

Bookmark

Authors

EREugen-Toma RaduLucian Blaga University of Sibiu NPNastaca Alina PaladeLucian Blaga University of Sibiu CSCrina Cristina SolomonLucian Blaga University of Sibiu

Discussion

Member takes

Implication

Randomized trial finds associations between microplastics in liver and fibrosis/inflammation in adults, indicating potential health impacts.

Key Points

This study aims to investigate the presence of suspected microplastic-like particles in human liver tissue and their correlations with various clinical measures.
Post-mortem liver tissue samples collected from 55 adults.
Microplastic-like particles extracted using hydrogen peroxide digestion and subsequent morphological assessments.
Statistical analyses included Mann–Whitney U tests, Fisher’s exact tests, and Spearman correlation analysis.
Suspected microplastic-like particles detected in 9 of 55 individuals (16.4%).
Lower ALT levels and leukocyte counts found in individuals with detected microplastic-like particles.
Weak positive correlation (95% CI) between microplastic-like particle burden and liver fibrosis/inflammation.

Cite This Study

Radu et al. (2026) studied this question.

synapsesocial.com/papers/6a7d76e62b0e0cff3f640a1c https://doi.org/10.3390/life16081315

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