January 1, 1982The Journal of Kansai Medical UniversityOpen Access

Hemodynamic Response to Volume Expansion in Ischemic Heart Disease

View Full Paper

Ask AI

Bookmark

Why the study?

Does volume expansion with hydroxyethyl starch reveal differences in cardiac reserve among patients with ischemic heart disease without overt heart failure?

Population

31 patients with ischemic heart disease without overt heart failure, subdivided into 5 groups according to…

Comparison

Volume expansion with 6% hydroxyethyl starch… vs Baseline hemodynamics prior to infusion (control).

Design

Cohort

Follow-up

Acute (during infusion)

Authors

HOHideki OnoyamaKansai Medical University TIToshiji IwasakaCardiac Imaging HYHiroshi YoshiokaKansai Medical University

Discussion

Member takes

Implication

Normal resting hemodynamics may mask impaired cardiac reserve after MI; leaves open whether volume challenge testing refines risk stratification in ischemic heart disease.

Structured PICO

Does volume expansion with hydroxyethyl starch reveal differences in cardiac reserve among patients with ischemic heart disease without overt heart failure?

Population

31 patients with ischemic heart disease (6 stable angina and 25 old myocardial infarction) without overt heart failure, subdivided into 5 groups according to ECG findings and clinical features in acute phase.

Intervention

Volume expansion with 6% hydroxyethyl starch infused at 20 ml/min, evaluated at every 100 ml up to a maximum of 400 ml or until pulmonary artery diastolic pressure reached 18 mmHg.

Comparator

Baseline hemodynamics prior to infusion (control).

Outcome

Hemodynamic response including pulmonary artery diastolic pressure (PADP), mean right atrial pressure (mRAP), cardiac index (CI), and slope of cardiac function curve.surrogate

Volume loading unmasks compromised cardiac reserve and right ventricular failure in ischemic heart disease patients who otherwise present with normal resting hemodynamics.

Cite This Study

Onoyama et al. (1982) studied this question.

synapsesocial.com/papers/6a7d7f166fa7f63de3912246 https://doi.org/10.5361/jkmu1956.34.4_982

View Full Paper

Ask AI

Bookmark

Implication

Normal resting hemodynamics may mask impaired cardiac reserve after MI; leaves open whether volume challenge testing refines risk stratification in ischemic heart disease.

Hemodynamic Response to Volume Expansion in Ischemic Heart Disease

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Hemodynamic Response to Volume Expansion in Ischemic Heart Disease

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider