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In vitro study demonstrates enhanced antiadhesive activity of glycoconjugate metal complexes against pathogens, indicating metal coordination boosts efficacy.
adhesion to buccal epithelial cells (both at 0.1 mM). The results presented demonstrate the potential for metal coordination to significantly enhance biological activity of glycoconjugates, surpassing the effect of the ligand's modest lectin-binding affinity alone.
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Wojtczak et al. (2025) studied this question.
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