Key result
The PPARα GG genotype was significantly more frequent in elite soccer players compared to motorcycle riders (OR 0.2753) and combat sport athletes.
Why the study?
Soccer, combat sports, and motorcycling share mixed metabolic predominance and diverse physical demands, prompting investigation into genetic markers to distinguish their predominant components.
Do allelic and genotype frequencies of ACE, ACTN3, CK-MM, and PPARα polymorphisms differ among elite athletes from soccer, combat sports, and motorcycling?
Population
113 professional athletes from motorcycling, soccer and combat sports
Comparison
Allelic and genotype frequencies compared among motorcycling, soccer, and combat sports athletes
Design
Genetic association study
Authors
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Does not support genetic screening for sport selection; leaves open PPARα as a hypothesis-generating marker for metabolic profiling in mixed disciplines.
Cross-Sectional (n=113)
Do allelic and genotype frequencies of ACE, ACTN3, CK-MM, and PPARα polymorphisms differ among elite athletes from soccer, combat sports, and motorcycling?
Odds Ratio: 0.2753 (95% CI 0.0963–0.7868)
Absolute Event Rate: 69.1% vs 38.1%
p-value: p=0.0310
The PPARα polymorphism may serve as a potential genetic marker to distinguish predominant metabolic components among mixed sport disciplines, with the G allele being more prevalent in soccer players.
Cocci et al. (2019) conducted a cross-sectional in Elite athletes (mixed sport disciplines) (n=113). PPARα GG genotype vs. Motorcycle riders and combat sport athletes was evaluated on PPARα GG genotype frequency (OR 0.2753, 95% CI 0.0963-0.7868, p=0.0310). The PPARα GG genotype was significantly more frequent in elite soccer players compared to motorcycle riders (OR 0.2753) and combat sport athletes.
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