Why the study?
Does ramipril reduce major cardiac events and improve left ventricular remodeling in intermediate-risk patients after CABG?
Population
n=130 intermediate-risk patients at a median of 7 days after coronary artery bypass grafting, with a mean…
Comparison
Ramipril commenced at a median of 7 days after… vs Placebo
Design
RCT, randomized
Follow-up
median of 33 months (range 12-46 months)
Authors
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Supports early ramipril post-CABG in intermediate-risk patients; extends ACEI evidence to this population with impaired LVEF.
Does ramipril reduce major cardiac events and improve left ventricular remodeling in intermediate-risk patients after CABG?
Ramipril significantly reduces major cardiac events and improves left ventricular remodeling when initiated early after CABG in intermediate-risk patients with moderately impaired LVEF.
Kjøller‐Hansen et al. (2003) studied this question.
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