Key result
A proinflammatory diet was not associated with an increased risk of total cardiovascular disease compared to an anti-inflammatory diet.
Why the study?
The dietary inflammatory index has been linked to CVD in several populations, but its association with CVD events needed evaluation in a representative population sample in northeastern Iran.
Does a proinflammatory diet (DII ≥ 0) increase the risk of incident cardiovascular disease compared to an anti-inflammatory diet in middle-aged Iranian adults?
Cohort (n=4,672)
Does a proinflammatory diet (DII ≥ 0) increase the risk of incident cardiovascular disease compared to an anti-inflammatory diet in middle-aged Iranian adults?
The dietary inflammatory index was not significantly associated with the risk of incident cardiovascular disease in a middle-aged Iranian cohort.
Answers are grounded in this paper and cite their sources.
No evidence to modify dietary advice; leaves open the DII-CVD link in Middle Eastern adults.
The dietary inflammatory index (DII) is a novel way of describing diet that has been studied in relation to various health conditions, including cardiovascular disease (CVD) in several populations. We aimed to investigate the association between DII and CVD events among a representative population sample in northeastern Iran. This prospective cohort study was a subsample of 4,672 adults aged 35-65 years, and recruited as part of Mashhad stroke and heart atherosclerotic disorder cohort study population. The DII was computed at baseline according to a 65-item validated food frequency questionnaire. Cox regression was used to determine the association of DII with incident CVD. One hundred twenty-four participants developed CVD (including 24 cases of myocardial infarction [MI], 34 cases of stable angina [SA], and 66 cases of unstable angina [UA]). After adjusting for potential confounding factors, a hazard ratios of 1.06 (95% confidence interval: 0.70-1.60), 1.36 (95% confidence interval: 0.52-3.52), 1.33 (95% confidence interval: 0.60-2.94), and 0.86 (95% confidence interval: 0.48-1.53) were found for total CVD, MI, SA, and UA events, respectively, among the participants with proinflammatory diet (DII ≥ 0) versus those with anti-inflammatory diet (DII < 0). There was no statistically significant association between the DII and total CVD, MI, SA, or UA in this population of middle-aged Iranian men and women.
No takes yet. Share an insight, caveat, or question.
Asadi et al. (2019) conducted a cohort in Cardiovascular disease (n=4,672). Proinflammatory diet (DII ≥ 0) vs. Anti-inflammatory diet (DII < 0) was evaluated on Total cardiovascular disease (CVD) events (HR 1.06, 95% CI 0.70-1.60). A proinflammatory diet was not associated with an increased risk of total cardiovascular disease compared to an anti-inflammatory diet.
Synapse has enriched 10 related papers. Consider them for comparative context: