Key result
A 90-year-old male with follicular lymphoma developed progressive cardiac involvement and severe heart failure, ultimately passing away after an episode of aspiration pneumonia.
Why the study?
Cardiac lymphoma has a low incidence and mainly occurs secondary to non-Hodgkin's lymphoma, particularly diffuse large B-cell lymphoma.
Case Report (n=1)
No
Cardiac involvement in follicular lymphoma is rare and can present with severe heart failure, carrying a poor prognosis.
Answers are grounded in this paper and cite their sources.
Rare cardiac involvement in follicular lymphoma may cause fatal HF; leaves open incidence, screening, and management questions.
BACKGROUND: The incidence of cardiac lymphoma is low, and it mainly occurs secondary to non-Hodgkin's lymphoma, particularly diffuse large B-cell lymphoma. Here, we report a case of follicular lymphoma with cardiac involvement and severe heart failure as the sole clinical manifestation. CASE SUMMARY: A 90-year-old male patient was first admitted to our hospital due to an accidentally discovered painless mass in the right lower abdomen. A biopsy of the mass revealed a follicular lymphoma. Positron emission tomography-computed tomography confirmed mild pericardial effusion, and echocardiography showed no structural abnormalities with normal ejection fraction at the time of diagnosis. The patient refused our recommendation of chemotherapy and was re-admitted 4 mo later due to heart failure. A series of subsequent echocardiographic examinations showed thickening of the left ventricular walls and increasing pericardial effusion over the following 2 mo. His heart failure exacerbated despite all symptomatic and supportive treatments. He passed away after an episode of aspiration pneumonia. CONCLUSION: The diagnosis of cardiac lymphoma is difficult as its clinical manifestations are nonspecific, and prognosis is poor.
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Sun et al. (2022) conducted a case report in Follicular lymphoma with cardiac involvement (n=1). Follicular lymphoma with cardiac involvement was evaluated on Disease progression and mortality. A 90-year-old male with follicular lymphoma developed progressive cardiac involvement and severe heart failure, ultimately passing away after an episode of aspiration pneumonia.
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