Key result
A 4-year-old boy with multifocal precursor B-cell lymphoblastic lymphoma and cardiac involvement successfully responded to 3 cycles of chemotherapy following diagnosis via multiple imaging modalities.
Why the study?
Lymphoma with cardiac involvement is a high-risk lesion, especially in children, with multifocal precursor B-cell lymphoblastic lymphoma presenting as a rare clinical entity.
Case Report (n=1)
No
Multimodality imaging is crucial for the early diagnosis and management of rare pediatric cases of multifocal precursor B-cell lymphoblastic lymphoma with cardiac involvement.
Multimodality imaging aided diagnosis in rare pediatric cardiac lymphoma; leaves open broader efficacy and requires validation.
Lymphoma with cardiac involvement is a high-risk lesion, especially in children. We report a rare clinical case of multifocal precursor B-cell lymphoblastic lymphoma in a child with cardiac involvement. A 4-year-old boy presented to the Vietnam National Children's Hospital with a vague headache, but magnetic resonance imaging of the head was normal. After 1 week, the patient showed symptoms of chest pain, fatigue, dyspnea, and abdominal pain. On transthoracic echocardiography and multislice computed tomography of the thorax, a mass was detected in the right atrial wall. Abdominal ultrasound showed a small bowel intussusception, multiple nodules in the intestinal wall, and mesenteric lymph nodes. Histopathology of the bowel confirmed the diagnosis of multifocal precursor B-cell lymphoblastic lymphoma. The patient responded to 3 cycles of chemotherapy for lymphoma. Therefore, combining multiple imaging methods allowed for early diagnosis and improved treatment.
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Ninh et al. (2021) conducted a case report in Multifocal precursor B-cell lymphoblastic lymphoma with cardiac involvement (n=1). Chemotherapy was evaluated on Response to treatment. A 4-year-old boy with multifocal precursor B-cell lymphoblastic lymphoma and cardiac involvement successfully responded to 3 cycles of chemotherapy following diagnosis via multiple imaging modalities.
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