Key result
A 12-year-old girl with a metastatic cardiac tumor from precursor B-cell lymphoblastic lymphoma initially responded to chemotherapy but experienced recurrence and died 8 months after diagnosis.
Why the study?
Cardiac involvement in metastatic tumors is not widely investigated, and diffuse metastasis to the myocardium and endocardium is uncommon and usually diagnosed post mortem.
Case Report (n=1)
This case highlights a rare presentation of metastatic precursor B-cell lymphoblastic lymphoma as severe heart failure in a child, illustrating the diagnostic and therapeutic challenges when malignancy is complicated by severe cardiomyopathy.
Cardiac involvement in metastatic tumors is not widely investigated. Commonest site of cardiac involvement is the pericardium. However, diffuse metastasis to the myocardium and endocardium is uncommon. Striated cardiac muscle, fast blood flow within the heart and unique lymphatic drainage make malignant metastasis to the heart rare. Cardiac metastasis is a late manifestation of malignancy and most of the cases are diagnosed on Post mortem. We describe a case of metastatic Pre B-Lymphoblastic Lymphoma in a child who presented with heart failure.
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Dorah et al. (2019) conducted a case report in Metastatic Cardiac Tumor from Precursor B Cell Lymphoblastic Lymphoma (n=1). Chemotherapy (Dexamethasone, Vincristine, Asparaginase) was evaluated on Clinical outcome. A 12-year-old girl with a metastatic cardiac tumor from precursor B-cell lymphoblastic lymphoma initially responded to chemotherapy but experienced recurrence and died 8 months after diagnosis.
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