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November 1, 1987Annals of Internal Medicine

The Automatic Implantable Cardioverter-Defibrillator in Drug-Refractory Ventricular Tachyarrhythmias

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Why the study?

Does the automatic implantable cardioverter-defibrillator prevent sudden death in patients with drug-refractory ventricular tachyarrhythmias?

Population

78 patients with symptomatic, sustained ventricular tachyarrhythmias that were previously drug-refractory.

Comparison

Automatic implantable cardioverter-defibrillator… vs Amiodarone alone

Design

Cohort

Follow-up

1 and 2 years

Authors

RFRichard N. FogorosDanville Community College

Discussion

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Overview

Supports ICD consideration in drug-refractory VT with syncope; leaves open randomized confirmation of survival benefit.

Structured PICO

Does the automatic implantable cardioverter-defibrillator prevent sudden death in patients with drug-refractory ventricular tachyarrhythmias?

P
Population
78 patients with symptomatic, sustained ventricular tachyarrhythmias that were previously drug-refractory.
I
Intervention
Automatic implantable cardioverter-defibrillator and amiodarone (for patients presenting with loss of consciousness)
C
Comparator
Amiodarone alone (for patients presenting with or without loss of consciousness)
O
Outcome
Sudden death at 1 and 2 yearshard clinical

The automatic implantable cardioverter-defibrillator significantly reduces the risk of sudden death in patients with drug-refractory ventricular tachyarrhythmias who present with loss of consciousness.

Cite This Study

Richard N. Fogoros (1987) studied this question.

synapsesocial.com/papers/6a7d91c5050e98c0187d81a4https://doi.org/10.7326/0003-4819-107-5-635
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinical experience, complications, and survival in 70 patients with the automatic implantable cardioverter/defibrillator.1985 · 452 citations
  2. 2The Automatic Implantable Cardioverter-Defibrillator: Efficacy, Complications, and Device Failures1986 · 258 citations
  3. 3Mortality in Patients with Implanted Automatic Defibrillators1983 · 313 citations
  4. 4Prevention of Sudden Arrhythmic Death with Implanted Automatic Defibrillators1982 · 26 citations
  5. 5Amiodarone-Induced Refractoriness to Cardioversion1984 · 89 citations