Key result
A novel cuffless blood-pressure estimation method achieved an accuracy of 0.73 ± 10.04 mmHg for SBP in hypertensive patients, reducing standard deviation error by 3 mmHg versus traditional algorithms.
Why the study?
Does a cuffless blood-pressure estimation method integrating HPSR improve estimation accuracy compared to traditional PTT-based algorithms in hypertensive and normotensive subjects?
Cross-Sectional (n=60)
Does a cuffless blood-pressure estimation method integrating HPSR improve estimation accuracy compared to traditional PTT-based algorithms in hypertensive and normotensive subjects?
Including autonomic activity factors like HPSR in cuffless BP estimation models improves accuracy, particularly for hypertensive patients.
Answers are grounded in this paper and cite their sources.
May enhance cuffless BP monitoring in hypertension; hypothesis-generating pending larger validation trials.
OBJECTIVE: Cuffless blood-pressure (BP) estimation has attracted widespread interest owing to its potential for long-term, non-invasive BP monitoring. But it is still impractical in clinical settings, mainly owing to ongoing challenges with respect to accuracy in hypertensive patients. To better estimate the BP, the current study proposes a new cuffless estimation method that includes a sympathetic tone, which has been reported with a varied pattern in hypertensive patients. APPROACH: First, the heart-rate variability of all subjects is investigated, and a new parameter, the heart-rate power spectrum ratio (HPSR), is proposed to indicate BP dynamics under sympathetic regulation. Then, a new BP estimation model is constructed by integrating HPSP with the pulse transit time (PTT) and photoplethysmography intensity ratio. The estimation accuracy is further evaluated by making comparisons with the standard sphygmomanometer BP on 60 subjects (29 hypertensive and 31 normotensive). MAIN RESULTS: A significant increase in HPSR was observed in hypertensive patients compared to normotensive subjects. Of the 60 subjects, the estimation accuracy was 0.73 ± 10.04 mmHg for systolic BP (SBP) and 0.90 ± 7.10 mmHg for diastolic BP (DBP) in hypertensive patients, which is comparable to 0.54 ± 7.52 mmHg for SBP and 0.82 ± 6.20 mmHg for DBP in normotensive subjects. Furthermore, the proposed method overperformed the traditional PTT-based algorithm by reducing the 3 mmHg error in the standard deviation in hypertensive patients. SIGNIFICANCE: The results of the current study demonstrate that the inclusion of factors associated with autonomic activities in the BP estimation model would improve the BP estimation accuracy, especially for hypertensive subjects.
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Chen et al. (2018) conducted a cross-sectional in Hypertension (n=60). Cuffless blood-pressure estimation method including heart-rate power spectrum ratio (HPSR) vs. Standard sphygmomanometer BP and traditional PTT-based algorithm was evaluated on Estimation accuracy for systolic and diastolic blood pressure. A novel cuffless blood-pressure estimation method achieved an accuracy of 0.73 ± 10.04 mmHg for SBP in hypertensive patients, reducing standard deviation error by 3 mmHg versus traditional algorithms.
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