Key result
Combination intervention treatment reduced 90-day mortality compared to medical treatment (23.5% vs 59.5%; p=0.012) in patients with concurrent cardio-cerebral infarction.
Why the study?
Concurrent acute ischemic stroke and acute myocardial infarction is an extremely rare and lethal emergency condition with unclear causes, prognosis, and optimal treatment.
Does combination intervention treatment reduce mortality in patients with concurrent cardio-cerebral infarction compared to medical treatment?
Population
94 cases from literature plus 2 additional cases with concurrent cardio-cerebral infarction
Comparison
Combination intervention treatment (PCI and mechanical thrombectomy) vs medical treatment
Design
Literature review, case series, and meta-analysis
Follow-up
90 days
Authors
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Supports combination intervention in cardio-cerebral infarction; extends limited Level 1 evidence for this rare dual emergency.
Meta-Analysis (n=94)
Yes
Does combination intervention treatment reduce mortality in patients with concurrent cardio-cerebral infarction compared to medical treatment?
Absolute Event Rate: 23.5% vs 59.5%
p-value: p=0.012
In patients with concurrent cardio-cerebral infarction, combination intervention with PCI and mechanical thrombectomy significantly reduces hospital and 90-day mortality compared to medical therapy alone.
Habib et al. (2023) conducted a meta-analysis in Concurrent cardio-cerebral infarction (n=94). Combination intervention treatment (percutaneous coronary intervention and mechanical thrombectomy) vs. Medical treatment was evaluated on 90-day mortality (p=0.012). Combination intervention treatment reduced 90-day mortality compared to medical treatment (23.5% vs 59.5%; p=0.012) in patients with concurrent cardio-cerebral infarction.
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