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March 17, 2009Annals of Internal Medicine

QTc Interval Screening in Methadone Treatment

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Why the study?

What are the recommended cardiac safety and QTc screening protocols for patients prescribed methadone?

Population

Patients prescribed methadone

Design

Guideline

Authors

MKMori J. KrantzAmerican College of Cardiology

Discussion

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Implication

May warrant routine ECG screening for all methadone patients; extends prior safety alerts into formal clinical guidelines.

Structured PICO

What are the recommended cardiac safety and QTc screening protocols for patients prescribed methadone?

P
Population
Patients prescribed methadone
I
Intervention
QTc interval screening (pretreatment ECG, follow-up ECG within 30 days and annually) and risk stratification
O
Outcome
Cardiac safety and arrhythmia risk mitigationsafety

This guideline establishes a standardized ECG screening and monitoring protocol to mitigate the risk of QTc prolongation and arrhythmias in patients receiving methadone.

Cite This Study

Mori J. Krantz (2009) conducted a review in Patients prescribed methadone. QTc interval screening was evaluated. An expert panel recommends pretreatment and follow-up electrocardiogram screening for all patients prescribed methadone to monitor QTc interval and mitigate arrhythmia risk.

synapsesocial.com/papers/6a7da110e5379bb2b27d853bhttps://doi.org/10.7326/0003-4819-150-6-200903170-00103
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