Key result
A high waist-to-height ratio was nonlinearly associated with a 1.45-fold increased risk of new-onset hypertension compared to a low waist-to-height ratio over a maximum 6-year follow-up.
Why the study?
The association between waist-to-height ratio and hypertension has not been adequately explained, including potential nonlinear associations in the general population.
Does a higher waist-to-height ratio predict the risk of new-onset hypertension in the general population?
Population
4,458 individuals from the China Health and Nutrition Survey
Comparison
Higher vs lower waist-to-height ratio
Design
Prospective cohort study
Follow-up
Maximum six-year follow-up period
Authors
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Supports waist-to-height ratio monitoring for hypertension risk stratification; leaves open causal effects and intervention benefits.
Cohort (n=4,458)
Yes
Does a higher waist-to-height ratio predict the risk of new-onset hypertension in the general population?
Hazard Ratio: 1.45 (95% CI 1.26–1.67)
Absolute Event Rate: 44.5% vs 21.5%
p-value: p=<0.001
Waist-to-height ratio demonstrates a U-shaped nonlinear association with the risk of new-onset hypertension and is superior to BMI in predicting hypertension risk in the general population.
Wang et al. (2023) conducted a cohort in New-onset hypertension (n=4,458). High waist-to-height ratio (WHtR) vs. Low waist-to-height ratio was evaluated on Incidence of new-onset hypertension (HR 1.45, 95% CI 1.26-1.67, p=<0.001). A high waist-to-height ratio was nonlinearly associated with a 1.45-fold increased risk of new-onset hypertension compared to a low waist-to-height ratio over a maximum 6-year follow-up.