January 1, 2004Circulation JournalOpen Access

Rationale and Design of a Large-Scale Trial Using Atrial Natriuretic Peptide (ANP) as an Adjunct to Percutaneous Coronary Intervention for ST-Segment Elevation Acute Myocardial Infarction-Japan-Working Groups of Acute Myocardial Infarction for the Reduction of Necrotic Damage by ANP (J-WIND-ANP)-

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Why the study?

Does intravenous atrial natriuretic peptide (ANP) reduce infarct size and improve left ventricular function in patients with acute myocardial infarction undergoing PCI?

Structured PICO

Does intravenous atrial natriuretic peptide (ANP) reduce infarct size and improve left ventricular function in patients with acute myocardial infarction undergoing PCI?

Population

Patients with acute myocardial infarction (AMI) who are candidates for percutaneous coronary intervention (PCI)

Intervention

Intravenous atrial natriuretic peptide (ANP) as an adjunctive therapy to PCI

Comparator

Placebo administration

Outcome

Estimated infarct size (Sigma creatine kinase and troponin T) and left ventricular function (left ventriculograms)surrogate

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

The J-WIND-ANP trial is designed to evaluate whether intravenous ANP as an adjunct to PCI reduces infarct size and improves LV function in AMI patients.

Cite This Study

Asakura et al. (2004) studied this question.

synapsesocial.com/papers/6a7da67377b363cb17b86fd6 https://doi.org/10.1253/circj.68.95

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Implication

The J-WIND-ANP trial is designed to evaluate whether intravenous ANP as an adjunct to PCI reduces infarct size and improves LV function in AMI patients.

Rationale and Design of a Large-Scale Trial Using Atrial Natriuretic Peptide (ANP) as an Adjunct to Percutaneous Coronary Intervention for ST-Segment Elevation Acute Myocardial Infarction-Japan-Working Groups of Acute Myocardial Infarction for the Reduction of Necrotic Damage by ANP (J-WIND-ANP)-

Structured PICO

Discussion

Implication

Cite This Study

Rationale and Design of a Large-Scale Trial Using Atrial Natriuretic Peptide (ANP) as an Adjunct to Percutaneous Coronary Intervention for ST-Segment Elevation Acute Myocardial Infarction-Japan-Working Groups of Acute Myocardial Infarction for the Reduction of Necrotic Damage by ANP (J-WIND-ANP)-

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider