Why the study?
Does intravenous ANP reduce exercise-induced myocardial ischemia in patients with stable effort angina pectoris?
Population
14 patients with stable effort angina pectoris
Comparison
Intravenous infusion of synthetic 28-amino acid… vs Intravenous infusion of saline during exercise…
Design
RCT, double-blind
Follow-up
Acute (during exercise testing)
Authors
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ANP infusion may lessen exercise ischemia in stable angina; confirms anti-ischemic effect in RCT and supports further development.
Does intravenous ANP reduce exercise-induced myocardial ischemia in patients with stable effort angina pectoris?
Intravenous ANP significantly attenuates exercise-induced myocardial ischemia and improves myocardial perfusion in patients with stable effort angina pectoris.
Lai et al. (1993) studied this question.
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