Key result
Wall motion score index measured by early postoperative cardiac CT significantly predicted all-cause death (OR 10.60) in patients who had undergone coronary artery bypass grafting.
Why the study?
The study evaluated the clinical utility of early postoperative cardiac CT for assessing LV function and predicting prognosis in patients after CABG.
Does early postoperative cardiac CT predict prognosis and evaluate left ventricular function comparably to echocardiography in patients who have undergone CABG?
Cohort (n=136)
No
Does early postoperative cardiac CT predict prognosis and evaluate left ventricular function comparably to echocardiography in patients who have undergone CABG?
Odds Ratio: 10.6017 (95% CI 2.1737–51.7063)
p-value: p=0.0035
Early postoperative cardiac CT provides comparable left ventricular functional assessment to echocardiography, and its wall motion score index independently predicts all-cause mortality and MACE after CABG.
We evaluated the clinical utility of early postoperative cardiac computed tomography (CT) for evaluating left ventricular (LV) function and predicting prognosis in patients who had undergone coronary artery bypass grafting (CABG). Of the 205 patients who underwent CABG from March 2011 to December 2014, 136 underwent early postoperative cardiac CT (within 30 days after CABG) and were enrolled as the study population. The baseline and postoperative follow-up echocardiographic findings, major adverse cardiac events (MACE), and death were recorded for a follow-up period (mean, 5.9 ± 1.1 years). Functional cardiac CT parameters were compared to echocardiographic measurements. The associations between cardiac CT findings and functional recovery and prognosis were evaluated by logistic regression analyses. The LVEF measured via cardiac CT was significantly higher (56.2 ± 11.5% vs. 61.9 ± 12.9%; p = 0.0002) compared to those via early postoperative echocardiography, but the wall motion score index (WMSI) was not significantly different (1.23 ± 0.33 vs. 1.21 ± 0.28, p = 0.5041) between the two methods. During the follow-up period, 17 patients (12.5%) died and 40 (29.4%) developed MACE. Both the LVEF and WMSI measured with early postoperative echocardiography (p = 0.0202 and odds ratio [OR] = 5.0171, p = 0.0039, respectively), and cardiac CT (OR = 0.9625, p = 0.0091 and OR = 14.3605, p = 0.0001, respectively) predicted MACE OR = 0.9630, but only the WMSI, measured using cardiac CT, predicted all-cause death (OR = 10.6017, p = 0.0035). In CABG patients, LVEF and the WMSI measured with early postoperative cardiac CT were comparable with echocardiography and predicted the development of MACE and all-cause death.
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Kang et al. (2020) conducted a cohort in Coronary artery disease post-coronary artery bypass grafting (n=136). Wall motion score index (WMSI) measured by early postoperative cardiac CT was evaluated on All-cause mortality (OR 10.6017, 95% CI 2.1737-51.7063, p=0.0035). Wall motion score index measured by early postoperative cardiac CT significantly predicted all-cause death (OR 10.60) in patients who had undergone coronary artery bypass grafting.
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