Tele-rehabilitation using transcranial direct current stimulation combined with exercise in people with spinal cord injury: a randomized controlled trial

Thanwarat Chantanachai; Irin Apiworajirawit; Pipat Klamruen; Benchaporn Aneksan; Paradee Auvichayapat; Alexandra Lackmy‐Vallée; Wanalee Klomjai

doi:10.2340/jrm.v57.42353

May 7, 2025Journal of Rehabilitation MedicineOpen Access

Tele-rehabilitation using transcranial direct current stimulation combined with exercise in people with spinal cord injury: a randomized controlled trial

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Key Points

To evaluate the efficacy of home-based transcranial direct current stimulation combined with tele-supervised exercise on motor and sensory recovery, spasticity, functional performance, and quality of life in individuals with spinal cord injury.
Prospective, double-blind, randomized, sham-controlled trial allocating 30 individuals with spinal cord injury to either active or sham transcranial direct current stimulation.
Participants received 12 sessions over 4 weeks (3 sessions/week), consisting of 20 minutes of stimulation followed by 1 hour of tele-supervised exercise.
Outcomes were evaluated at baseline, post-intervention, and at a 1-month follow-up using the International Standards for Neurological Classification of Spinal Cord Injury alongside secondary measures of strength, spasticity, independence, and quality of life.
A significant group-by-time interaction emerged for upper extremity motor scores (F(1,18) = 4.49, p = 0.043; main effect of time F(1,18) = 7.82, p = 0.009).
Post-hoc testing revealed significant upper extremity motor score improvement exclusively in the active stimulation group at the 1-month follow-up (p = 0.002).
No statistically significant differences occurred between groups for sensory scores, spasticity, functional independence, transfer ability, or quality of life.

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Implication

Randomized double-blind trial demonstrates upper-limb motor improvements from home tDCS combined with exercise in spinal cord injury, indicating potential for remote neurorehabilitation.

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Cite This Study

Chantanachai et al. (2025) studied this question.

synapsesocial.com/papers/6a7db0fc4d9a7e00d75c9c4f https://doi.org/10.2340/jrm.v57.42353

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Tele-rehabilitation using transcranial direct current stimulation combined with exercise in people with spinal cord injury: a randomized controlled trial

Key Points

No abstract yet

Implication

Discussion

Cite This Study

Tele-rehabilitation using transcranial direct current stimulation combined with exercise in people with spinal cord injury: a randomized controlled trial

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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