Why the study?
Primary angiosarcoma of the breast presents diagnostic and management challenges due to unclear pathogenesis, lacking consensus on optimal treatment, and controversy surrounding adjuvant therapies.
Population
A teenager with thalassemia and primary angiosarcoma of the breast
Comparison
Complete surgical excision followed by incomplete chemotherapy
Design
Case report and comprehensive review
Follow-up
1-year
Key result
Complete surgical excision of primary breast angiosarcoma in a teenager resulted in no recurrence or metastasis at 1 year, despite the inability to complete adjuvant chemotherapy.
Authors
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Single case supports exploring surgery-alone strategies in breast angiosarcoma; leaves open need for prospective validation before practice change.
Case Report (n=1)
Complete surgical excision may be sufficient for 1-year recurrence-free survival in primary angiosarcoma of the breast even when adjuvant chemotherapy cannot be completed.
Han et al. (2024) conducted a case report in Primary angiosarcoma of the breast (n=1). Complete surgical excision was evaluated on Recurrence or metastasis. Complete surgical excision of primary breast angiosarcoma in a teenager resulted in no recurrence or metastasis at 1 year, despite the inability to complete adjuvant chemotherapy.