Key result
Selective cholesterol screening during school enrolment examinations identified 9 out of 133 tested children (6.8%) with elevated cholesterol levels indicative of familial hypercholesterolemia.
Why the study?
Familial hypercholesterolemia is underdiagnosed and undertreated, and childhood may be the optimal period for screening to ensure early detection and treatment of increased cardiovascular disease risk.
Does selective screening by school physicians improve the early detection of familial hypercholesterolemia in pre-school children?
Cross-Sectional (n=18,152)
Yes
Does selective screening by school physicians improve the early detection of familial hypercholesterolemia in pre-school children?
Selective screening for familial hypercholesterolemia during school enrolment examinations is a feasible strategy to identify affected children for early intervention.
No takes yet. Share an insight, caveat, or question.
Supports selective school screening feasibility for familial hypercholesterolemia; leaves open need for prospective validation before practice change.
Kreissl et al. (2019) conducted a cross-sectional in Familial hypercholesterolemia (n=18,152). Selective cholesterol screening was evaluated on Positive cholesterol screening (non-HDL-C > 160 mg/dL and/or LDL-C > 130 mg/dL). Selective cholesterol screening during school enrolment examinations identified 9 out of 133 tested children (6.8%) with elevated cholesterol levels indicative of familial hypercholesterolemia.
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