This contribution presents a combination of high-pressure liquid chromatography (HPLC) with a Raman spectrometer. With this approach, we have identified both isomer m-xylene and isomer p-xylene in solution at concentrations down to 10 −5 mol/L. The setup was developed to analyze compounds that cannot be separated by using standard HPLC techniques.
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Steinert et al. (1997) studied this question.
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