September 1, 1973Cardiovascular Research

Effect of intravenous prolactin infusion on arterial blood pressure in rabbits

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Why the study?

Does intravenous prolactin infusion increase arterial blood pressure in decerebrate rabbits?

Population

Decerebrate rabbits

Comparison

Intravenous infusion of prolactin at rates of 10… vs Intravenous infusion of saline only

Design

Preclinical

Follow-up

4 hours

Authors

DHD. F. HorrobinUniversity of Nairobi MMM.S. MankuAmarin (United Kingdom)PBP. G. BurstynUniversity of Zimbabwe

Discussion

Member takes

Implication

Does not inform clinical decisions; hypothesis-generating for prolactin's pressor effects in mammals.

Structured PICO

Does intravenous prolactin infusion increase arterial blood pressure in decerebrate rabbits?

Population

Decerebrate rabbits

Intervention

Intravenous infusion of prolactin at rates of 10 μg/kg/hr, 20 μg/kg/hr, and 50 μg/kg/hr

Comparator

Intravenous infusion of saline only

Outcome

Arterial blood pressure after 4 hours of infusionsurrogate

Intravenous prolactin infusion dose-dependently increases arterial blood pressure in a decerebrate rabbit model.

Cite This Study

Horrobin et al. (1973) studied this question.

synapsesocial.com/papers/6a7db9bcfa78bd2571186cc3 https://doi.org/10.1093/cvr/7.5.585

View Full Paper

Ask AI

Bookmark

Effect of intravenous prolactin infusion on arterial blood pressure in rabbits

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Effect of intravenous prolactin infusion on arterial blood pressure in rabbits

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider