Key result
Angina pectoris patients in NYHA class III/IV had a significantly higher risk of depression compared to those in NYHA class I (OR 3.94).
Why the study?
The influence of disease severity on mood symptoms in CHD is unknown, and the specific associations of mood symptoms with NYHA classes remain unexplored.
Population
443 consecutive inpatients with angina pectoris confirmed by angiography
Comparison
Mood symptoms across NYHA functional classes
Design
Cross-sectional study
Authors
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NYHA III/IV angina warrants depression screening in practice; cross-sectional data leaves open causality and intervention effects.
Cross-Sectional (n=443)
No
Odds Ratio: 3.94 (95% CI 2.11–7.36)
p-value: p=<0.001
In patients with angina pectoris, severe physical limitation (NYHA III/IV) is strongly associated with an increased risk of depression compared to mild or no limitation.
Yin et al. (2019) conducted a cross-sectional in Angina pectoris (n=443). NYHA functional class III/IV vs. NYHA functional class I was evaluated on Risk of depression (ordinal model) (OR 3.94, 95% CI 2.11-7.36, p=<0.001). Angina pectoris patients in NYHA class III/IV had a significantly higher risk of depression compared to those in NYHA class I (OR 3.94).
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