Why the study?
Does the double Master's two-step test accurately detect or exclude severe obstructive coronary atherosclerosis compared to selective coronary angiography in men with known or suspected CAD?
Population
160 men with known or suspected coronary artery disease, mean age 41.6 years. 90 subjects had no cardiac…
Comparison
Double Master's two-step test vs Selective coronary angiograms; 87 subjects also…
Design
Cross-sectional
Authors
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High false-positive and false-negative rates warrant caution against relying on the double Master's test; leaves open its diagnostic role pending higher-quality studies.
Does the double Master's two-step test accurately detect or exclude severe obstructive coronary atherosclerosis compared to selective coronary angiography in men with known or suspected CAD?
The double Master's two-step test has unacceptably high false positive and false negative rates, demonstrating that reliance on it to exclude severe coronary artery disease is unwarranted.
Gerald M. FitzGibbon (1971) studied this question.
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