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July 1, 1991Journal of neurosurgery

Electrothrombosis of saccular aneurysms via endovascular approach

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Why the study?

Does endovascular electrothrombosis using a detachable platinum coil achieve permanent occlusion of experimental saccular aneurysms in swine?

Population

11 experimental saccular aneurysms created on the common carotid artery of swine

Design

Preclinical

Follow-up

2 to 6 months

Authors

FVFernando ViñuelaUniversity of Southern CaliforniaISI SepetkaUniversity of Wisconsin–MadisonVMVelio MacellariIstituto Superiore di Sanità

Discussion

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Overview

Hypothesis-generating in swine; leaves open translation to durable human aneurysm occlusion.

Structured PICO

Does endovascular electrothrombosis using a detachable platinum coil achieve permanent occlusion of experimental saccular aneurysms in swine?

P
Population
11 experimental saccular aneurysms created on the common carotid artery of swine
I
Intervention
Endovascular electrothrombosis using a detachable platinum coil delivered through a microcatheter, with application of a low positive direct electric current to initiate thrombosis and detach the coil
O
Outcome
Permanent aneurysm occlusion and patency of the parent artery assessed by control angiogramssurrogate

Endovascular electrothrombosis using a detachable platinum coil successfully occluded experimental saccular aneurysms in a swine model, paving the way for clinical application.

Cite This Study

Viñuela et al. (1991) studied this question.

synapsesocial.com/papers/6a7dbc8010b6f5f3737d8d7chttps://doi.org/10.3171/jns.1991.75.1.0001
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Electrothrombosis of carotid-cavernous fistula1975 · 154 citations
  2. 2ELECTROTHERMIC COAGULATION OF AORTIC ANEURYSMS1938 · 80 citations