Key result
A 53-year-old female patient experienced three recurrent episodes of takotsubo cardiomyopathy over 4 years, including one rare inverted form, with full cardiac function restored after each episode.
Case Report (n=1)
This case highlights the rare occurrence of recurrent takotsubo cardiomyopathy, including the inverted form, and suggests a potential role for mental health management in preventing recurrence.
Recurrent takotsubo with full recovery supports vigilance in follow-up; leaves open mental health interventions for prevention.
Background: Takotsubo cardiomyopathy (TC) is a disease that causes transient left ventricular (LV) dysfunction in multiple vascular territories in the absence of coronary artery disease. Takotsubo cardiomyopathy is typically associated with dilation and dyskinesia of the apical and mid-LV segments induced by acute emotional and/or physical stress. Here, we present a case of recurrent TC including one episode of inverted TC, which is a rare form where dyskinesia occurs in the basal segments with sparing of the apical segments. Case summary: A 53-year-old female patient with a background history of chronic stress and anxiety was admitted with three episodes of recurrent TC over 4 years. The first episode in 2017 was triggered by an acute stressful event, but no major triggers were identified for the subsequent episodes. Although the first and third episodes displayed the signs of classical TC, the second episode was an inverted TC. Full cardiac function was restored after each episode. She now takes prognostic heart failure medications long term and mental health teams are trying to support her emotional wellbeing. Discussion: This patient displayed a rare disease course involving three recurrent episodes of TC, including one instance of its inverted form. Although psychiatric conditions and emotional stress are acknowledged as risk factors for TC, further research is needed to assess whether mental health treatment following TC can prevent disease recurrence.
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Carey et al. (2022) conducted a case report in Takotsubo cardiomyopathy (n=1). A 53-year-old female patient experienced three recurrent episodes of takotsubo cardiomyopathy over 4 years, including one rare inverted form, with full cardiac function restored after each episode.
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