Population
Humans (focus on skeletal muscle microvascular networks in the context of aging)
Design
Review
Authors
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Impaired upstream vasomotor responses in aging may reduce perfusion reserve; leaves open the impact of preserved topology on clinical outcomes.
Aging impairs the functional capacity of skeletal muscle microvascular networks to transmit vasomotor signals, despite structural branching topology remaining largely unchanged.
Shawn E. Bearden (2006) studied this question.
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