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Acute aortic dissection carries an extremely high early mortality if untreated, and survivors remain at long-term risk of death from ruptured aortic aneurysm.
ortic dissection may be fatal without early diagnosis and appropriate medical, surgical, or endovascular treatment.The presenting symptoms and signs are so myriad and nonspecific that dissection may be overlooked initially in up to 40% of cases.In addition, the diagnosis is established only postmortem in a substantial number of cases. 1 Few other conditions demand such prompt diagnosis and treatment, because the mortality rate of untreated dissection approaches 1%/h during the first 48 hours, 80% at 14 days, and 90% at three months. 2If unrecognized and untreated, fewer than 10% of patients with proximal aortic dissection survive a year.Most patients succumb within the first 3 months, 3 usually of acute aortic insufficiency, major branch vessel occlusion, or rupture into the pericardium, mediastinum, or left hemithorax.In 20 years of follow-up of 527 patients with aortic dissection, nearly 30% of late deaths were due to ruptured aortic aneurysm.
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Olin et al. (2003) studied this question.
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