Population
16 conscious rabbits implanted with a Doppler flow probe and renal nerve electrode
Comparison
Breathing hypoxic gas mixtures to induce… vs Renal-denervated rabbits exposed to hypoxia, and…
Design
Preclinical
Follow-up
4-9 days after surgery
Authors
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May implicate renal nerves in hypoxia-induced vasoconstriction; hypothesis-generating and leaves open human translation.
In conscious rabbits, high-frequency oscillations of renal sympathetic nerve activity contribute to vasoconstrictor tone, while lower frequencies contribute to renal blood flow variability.
Janssen et al. (1997) studied this question.
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