Why the study?
Can contrast-enhanced ultrasound (CEUS) imaging quantify adventitial vasa vasorum density to identify early atherosclerosis in a rabbit model?
Population
60 New Zealand white adult male rabbits, including 30 fed a high-fat diet for 4, 8, or 12 weeks, 20 fed a…
Comparison
Contrast-enhanced ultrasound imaging of the… vs Histopathological analysis and normal chow…
Design
Preclinical, analysed off-line using customized CEUS imaging software by an…
Follow-up
up to 12 weeks
Authors
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Suggests contrast-enhanced ultrasound may non-invasively identify early atherosclerotic neovascular.
Can contrast-enhanced ultrasound (CEUS) imaging quantify adventitial vasa vasorum density to identify early atherosclerosis in a rabbit model?
CEUS imaging can non-invasively quantify adventitial vasa vasorum density, which correlates with histological neovascularization and may serve as a marker for early atherosclerosis.
Li et al. (2017) studied this question.
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