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April 10, 2012Clinical Autonomic ResearchOpen Access

Sympathetic nerve activity in stress-induced cardiomyopathy

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Population

12 female patients with stress-induced cardiomyopathy and 12 healthy age, gender and BMI matched controls.

Design

Case-control

Authors

YSYrsa Bergmann SverrisdóttirTSTomas SchultzEÖElmir Ömerovic

Discussion

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Overview

Sympathetic inhibition may occur rapidly after acute SIC; leaves open its causal role and any therapeutic implications pending prospective studies.

Structured PICO

P
Population
12 female patients with stress-induced cardiomyopathy (SIC) (5 in acute phase 24-48 h, 7 in recovery phase 1-6 months) and 12 healthy age, gender and BMI matched controls.
C
Comparator
12 healthy age, gender and BMI matched controls
O
Outcome
Muscle sympathetic nerve activity (MSNA) expressed as burst frequency (BF), burst incidence (BI) and relative median burst amplitude (RMBA %)surrogate

Sympathetic neuronal outflow to the muscle vascular bed is lower in patients with stress-induced cardiomyopathy compared to healthy controls, suggesting rapid sympathetic inhibition following the initial acute phase.

Limitations

  • Small number of subjects in each group

Cite This Study

Sverrisdóttir et al. (2012) studied this question.

synapsesocial.com/papers/6a7dceb1968fa26fcacb510bhttps://doi.org/10.1007/s10286-012-0162-x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Neurohumoral Features of Myocardial Stunning Due to Sudden Emotional Stress2005 · 3,132 citations
  2. 2Plasma noradrenaline correlates to sympathetic muscle nerve activity in normotensive man1981 · 321 citations
  3. 3Impairment of Thermoregulatory Control of Skin Sympathetic Nerve Traffic in the Elderly2003 · 95 citations
  4. 4Mental stress is a cause of cardiovascular diseases: from scepticism to certainty2008 · 28 citations
  5. 5Renal noradrenaline spillover correlates with muscle sympathetic activity in humans.1996 · 166 citations