Key result
CT pulmonary angiogram reliably assessed treatment efficacy for acute pulmonary embolism, showing significant changes in pulmonary emboli number and obstruction index (P < .05).
Why the study?
Does CT pulmonary angiogram reliably assess treatment outcomes in patients with acute pulmonary embolism?
Observational (n=28)
Does CT pulmonary angiogram reliably assess treatment outcomes in patients with acute pulmonary embolism?
p-value: p=<.05
CT pulmonary angiogram is a reliable imaging modality for assessing the treatment efficacy of acute pulmonary embolism by tracking changes in emboli burden and pulmonary artery obstruction.
CTPA may aid PE treatment monitoring in observational data; leaves open prospective validation before practice change.
OBJECTIVE: To discuss the value of CT pulmonary angiogram (CTPA) for assessing the treatment outcome of acute pulmonary embolism (APE). MATERIALS AND METHODS: CT pulmonary angiogram data and other clinical data were collected for 28 cases diagnosed as APE and analyzed retrospectively. The number and positions of emboli in the pulmonary artery, pulmonary artery obstruction index, right ventricular/left ventricular diameter ratio, main pulmonary artery/ascending aorta diameter ratio and blood oxygen saturation, and pulmonary arterial pressure were compared before and after treatment. RESULTS: Of 28 cases, emboli in the pulmonary artery completely or partially disappeared in 16 and 12 cases, respectively. CPTA indicated that the pulmonary arterial pressure decreased dramatically and the blood oxygen saturation increased after treatment in 26 cases. There were significant differences in the number and positions of pulmonary emboli and in pulmonary artery obstruction index before and after treatment in 28 cases (P < .05). However, no significant differences were found in the right ventricular/left ventricular diameter ratio or main pulmonary artery/ascending aorta diameter ratio (P > .05). CONCLUSION: CT pulmonary angiogram proved reliable for assessing the treatment efficacy of APE, providing more clinical information on the patients' status.
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Zhou et al. (2017) conducted an observational in Acute pulmonary embolism (n=28). CT pulmonary angiogram (CTPA) vs. Pre-treatment baseline was evaluated on Number and positions of pulmonary emboli and pulmonary artery obstruction index (p=<.05). CT pulmonary angiogram reliably assessed treatment efficacy for acute pulmonary embolism, showing significant changes in pulmonary emboli number and obstruction index (P < .05).
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