Key result
Acute pulmonary embolism severity in older adults was inversely correlated with the left-to-right diameter (r = -0.477) and its product with the anteroposterior diameter (r = -0.557) of the left atrium.
Why the study?
To investigate changes in computed tomography pulmonary angiography (CTPA)-derived parameters in older adults with acute pulmonary embolism (APE).
Do CTPA-derived left atrial and left ventricular parameters correlate with the severity of acute pulmonary embolism in older adults?
Observational (n=267)
Do CTPA-derived left atrial and left ventricular parameters correlate with the severity of acute pulmonary embolism in older adults?
Effect estimate: r = -0.557
In older adults with acute pulmonary embolism, increased pulmonary artery obstruction is associated with smaller left atrial and left ventricular dimensions on CTPA, which may aid in risk stratification.
CTPA LA/LV parameters may differ by PAOI in older APE patients; leaves open prognostic utility pending prospective validation.
OBJECTIVE: This study aimed to investigate changes of computed tomography pulmonary angiography (CTPA)-derived parameters in older adults with acute pulmonary embolism (APE). METHODS: According to the pulmonary artery obstruction index (PAOI), patients with APE were divided into the A1 (PAOI ≥30%, n = 57) and A2 (PAOI <30%, n = 40) groups. Participants without APE were placed in group B (n = 170). The left atrial (LA) and left ventricular (LV) parameters among the three groups were compared, and the parameter changes in the 44 patients with APE were analyzed before and after treatment. The correlation between APE severity and the parameters was analyzed using correlation analysis. RESULTS: The left-to-right diameters (LR) of LA, and LR × anteroposterior diameters (AP) of LA and LV: A1 < A2 < B; LR of LV: A1 < A2, B; AP of LA and LV: A1, A2 < B. After treatment, LR and LR × AP of the LA and LV were significantly increased in the group A1 and LR of the LV and LR × AP of the LA and LV were elevated in the group A2. Acute pulmonary embolism severity was closely associated with LR × AP ( r = -0.557) and LR ( r = -0.477) of LA. CONCLUSIONS: With an increase in the degree of obstruction, older adults had a smaller LA and LV. Furthermore, the LR and LR × AP values of the LA were significantly decreased. These results contribute to in-time risk stratification.
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Zeng et al. (2023) conducted an observational in Acute pulmonary embolism (n=267). Acute pulmonary embolism severity (pulmonary artery obstruction index) vs. Participants without acute pulmonary embolism or with lower obstruction index was evaluated on Correlation between acute pulmonary embolism severity and left atrial/ventricular parameters (r = -0.557). Acute pulmonary embolism severity in older adults was inversely correlated with the left-to-right diameter (r = -0.477) and its product with the anteroposterior diameter (r = -0.557) of the left atrium.
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