Efficacy and safety of oral MK-954 (DuP 753), an angiotensin receptor antagonist, in essential hypertension

Edward Nelson; David Merrill; C. Sweet; Thomas E. Bradstreet; Deborah Panebianco; Richard L. Byyny; Theodore S. Herman; Kenneth C. Lasseter; Bernard Lévy; Geoffrey Lewis; F. Gilbert McMahon; R. Reeves; D Ruff; Andrew J. Shepherd; D.J. Weidler; John D. Irvin

doi:10.1097/00004872-199112000-00300

December 1, 1991Journal of Hypertension

Efficacy and safety of oral MK-954 (DuP 753), an angiotensin receptor antagonist, in essential hypertension

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Key Points

Evaluate the clinical efficacy and safety profile of the oral angiotensin receptor antagonist MK-954 (DuP 753) in patients diagnosed with essential hypertension.
Assessed oral administration of the selective angiotensin receptor antagonist MK-954 (DuP 753) in a cohort presenting with essential hypertension.
Monitored therapeutic efficacy in lowering blood pressure alongside systematic recording of drug-related adverse effects.
Quantitative clinical trial endpoints, per-arm event rates, and relative risk metrics are not specified in the publication text.
Evaluated the blood pressure-lowering response and tolerability of oral MK-954 as a targeted antihypertensive intervention.

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Implication

Clinical evaluation assesses the efficacy and safety of oral MK-954 in essential hypertension, indicating its therapeutic role in blood pressure regulation.

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Nelson et al. (1991) studied this question.

synapsesocial.com/papers/6a7dd0371a9d4ca5f9ac86af https://doi.org/10.1097/00004872-199112000-00300

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Efficacy and safety of oral MK-954 (DuP 753), an angiotensin receptor antagonist, in essential hypertension

Key Points

No abstract yet

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Implication

Discussion

Cite This Study

Efficacy and safety of oral MK-954 (DuP 753), an angiotensin receptor antagonist, in essential hypertension

Key Points

No abstract yet

Ask about this paper

Implication

Discussion

Cite This Study

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