Why the study?
Is the thiazide-sensitive Na,Cl-cotransporter (TSC) gene associated with polygenic hypertension susceptibility?
Is the thiazide-sensitive Na,Cl-cotransporter (TSC) gene associated with polygenic hypertension susceptibility?
The thiazide-sensitive Na,Cl-cotransporter (TSC) gene does not appear to have a primary role in the pathogenesis of polygenic hypertension in the studied rat and human cohorts.
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TSC variants not linked to hypertension in rat or human cohorts; leaves open roles for other ion transporters in polygenic hypertension.
Song et al. (2001) studied this question.
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