Why the study?
The study was conducted to investigate the expression of platelet-derived growth factor receptor alpha (PDGFR-alpha) in patients with valvular atrial fibrillation.
PDGFR-α expression is significantly upregulated in the right atrial tissue of patients with valvular atrial fibrillation, suggesting a potential role in atrial structural remodeling and fibrosis.
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PDGFR-α upregulation in valvular AF tissue supports fibrosis pathway research; leaves open any clinical role pending prospective trials.
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Su et al. (2023) studied this question.
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