Why the study?
Does a heparin-grafted HD membrane reduce the required systemic heparin dose and anti-Xa activity in stable hemodialysis patients?
Population
45 stable hemodialysis (HD) patients
Comparison
Heparin-grafted HD membrane with stepwise weekly… vs Baseline ordinary heparin dose
Design
Cohort
Authors
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Heparin-grafted membranes were associated with lower systemic heparin doses in stable HD; hypothesis-generating and requires randomized confirmation before practice change.
Does a heparin-grafted HD membrane reduce the required systemic heparin dose and anti-Xa activity in stable hemodialysis patients?
The use of a heparin-grafted membrane allows for significant reduction of systemic heparin dose and anti-Xa activity in stable hemodialysis patients, potentially reducing bleeding risk.
Kessler et al. (2012) studied this question.
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