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June 23, 2011Journal of Pediatric Gastroenterology and Nutrition

Biochemical Parameters and Anthropometry Predict NAFLD in Obese Children

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Why the study?

Does a predictive model combining biochemical parameters and anthropometry accurately predict NAFLD in obese children?

Population

56 obese 10-year-old children

Design

Cross-sectional

Authors

CMClaudio MaffeisUniversity of VeronaCBClaudia BanzatoUniversity of VeronaFRFrancesca RigottiUniversity of Rome Tor Vergata

Discussion

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Implication

May aid noninvasive NAFLD risk stratification in obese children; leaves open need for prospective validation before clinical use.

Structured PICO

Does a predictive model combining biochemical parameters and anthropometry accurately predict NAFLD in obese children?

P
Population
56 obese 10-year-old children
I
Intervention
Predictive model combining waist-to-height ratio, homeostasis model assessment of insulin resistance, adiponectin, and alanine aminotransferase
O
Outcome
Prediction of nonalcoholic fatty liver disease (NAFLD) diagnosed by magnetic resonance imagingsurrogate

A predictive equation using routinely available clinical and biochemical variables can accurately identify obese children at high risk for NAFLD.

Cite This Study

Maffeis et al. (2011) studied this question.

synapsesocial.com/papers/6a7de6ca02c864aefccb4f46https://doi.org/10.1097/mpg.0b013e31822960be
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