Why the study?
Does terlipressin improve systolic arterial pressure in vascular surgical patients with refractory hypotension who are chronically treated with ACE inhibitors or ARBs?
Population
51 consecutive vascular surgical patients chronically treated with angiotensin-converting enzyme inhibitors…
Design
Cohort
Follow-up
perioperative period (up to 6 minutes post-injection)
Authors
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May support terlipressin for refractory hypotension in ACEi/ARB vascular surgery patients; leaves open randomized confirmation of outcomes.
Does terlipressin improve systolic arterial pressure in vascular surgical patients with refractory hypotension who are chronically treated with ACE inhibitors or ARBs?
Terlipressin effectively and rapidly corrects intraoperative refractory hypotension in patients on chronic renin-angiotensin system antagonists without impairing left ventricular function.
Eyraud et al. (1999) studied this question.
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