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October 1, 2020Journal of Atrial FibrillationOpen Access

Adjunctive Vein of Marshall Ethanol Infusion During Atrial Fibrillation Ablation: A Systematic Review and Meta-Analysis

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Why the study?

Catheter ablation for AF can have limited efficacy, and the autonomic innervation of the vein of Marshall makes it an attractive adjunctive target.

Does adjunctive vein of Marshall ethanol infusion reduce late atrial fibrillation or atrial tachycardia recurrence in patients undergoing atrial fibrillation ablation?

Population

804 AF patients across four studies

Comparison

VOM-EI plus CA vs CA alone

Design

Systematic review and meta-analysis

Follow-up

≥3 months

Discussion

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Overview

May support adjunctive VOM-EI in AF ablation; confirms reduced late recurrence across pooled studies.

Structured PICO

Does adjunctive vein of Marshall ethanol infusion reduce late atrial fibrillation or atrial tachycardia recurrence in patients undergoing atrial fibrillation ablation?

P
Population
4 studies including 804 patients with atrial fibrillation (68.2% persistent AF), mean age 63.5±9.9 years.
I
Intervention
Adjunctive ethanol infusion of the vein of Marshall (VOM-EI) plus catheter ablation
C
Comparator
Catheter ablation alone
O
Outcome
Late (≥3 months) atrial fibrillation or atrial tachycardia recurrencecomposite

Adjunctive vein of Marshall ethanol infusion during AF ablation significantly reduces late AF/AT recurrence and improves acute mitral isthmus block without increasing procedural complications.

Cite This Study

A 2020 study studied this question.

synapsesocial.com/papers/6a7deed11a9d4ca5f9ac8e24https://doi.org/10.4022/jafib.20200492
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