Why the study?
Do psychotropic drugs induce transient ST segment elevation in right precordial leads resembling Brugada syndrome?
Do psychotropic drugs induce transient ST segment elevation in right precordial leads resembling Brugada syndrome?
Psychotropic drugs can induce transient Brugada-like ST segment elevation in right precordial leads, which may not be reproducible with flecainide.
Psychotropic drugs may induce transient Brugada-like ECG changes; this Level 5 observation is hypothesis-generating and should not yet change practice.
Psychotropic Drugs and ST Segment Elevation. Transient ST segment elevation in right precordial leads with use of psychotropic drugs is reported in two cases of overdose and one case of therapeutic administration. Flecainide did not reproduce ST segment elevation. The relationship of these abnormalities to the Brugada syndrome and the electrophysiologic hypothesis are discussed.
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Rouleau et al. (2001) studied this question.
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