What question did this study set out to answer?

To evaluate the engineering, biological mechanisms, and therapeutic applications of cell membrane-coated biomimetic nanoparticle delivery systems.

May 30, 2025Materials Today BioOpen Access

Stealth missiles with precision guidance: A novel multifunctional nano-drug delivery system based on biomimetic cell membrane coating technology

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Authors

YZYuyan Zhou XWXinyue Wang XTXiaorong Tian

Discussion

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Overview

Review demonstrates biomimetic cell membrane coatings enhance nanoparticle circulation and precision targeting in disease models, highlighting their broad clinical potential.

Key Points

To evaluate the engineering, biological mechanisms, and therapeutic applications of cell membrane-coated biomimetic nanoparticle delivery systems.
Synthesized evidence on key manufacturing steps and surface functionalization strategies for cell membrane-coated delivery platforms.
Assessed performance profiles across membrane sources, including erythrocytes, leukocytes, platelets, dendritic cells, cancer cells, and bacteria.
Membrane-coated nanocarriers effectively replicate source-cell biointerfaces, driving reticuloendothelial system evasion, prolonged systemic circulation, and barrier transit.
Preclinical findings confirm enhanced targeted biodistribution and therapeutic efficacy in oncology, ischemic stroke, and chronic inflammatory conditions.

Cite This Study

Zhou et al. (2025) studied this question.

synapsesocial.com/papers/6a7df414cf7e8b32dacb5a4a https://doi.org/10.1016/j.mtbio.2025.101922

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May 30, 2025Materials Today BioOpen Access

Stealth missiles with precision guidance: A novel multifunctional nano-drug delivery system based on biomimetic cell membrane coating technology

View Full Paper

Ask AI

Bookmark

Authors

YZYuyan Zhou XWXinyue Wang XTXiaorong Tian

Discussion

Member takes

Overview

Review demonstrates biomimetic cell membrane coatings enhance nanoparticle circulation and precision targeting in disease models, highlighting their broad clinical potential.

Key Points

To evaluate the engineering, biological mechanisms, and therapeutic applications of cell membrane-coated biomimetic nanoparticle delivery systems.
Synthesized evidence on key manufacturing steps and surface functionalization strategies for cell membrane-coated delivery platforms.
Assessed performance profiles across membrane sources, including erythrocytes, leukocytes, platelets, dendritic cells, cancer cells, and bacteria.
Membrane-coated nanocarriers effectively replicate source-cell biointerfaces, driving reticuloendothelial system evasion, prolonged systemic circulation, and barrier transit.
Preclinical findings confirm enhanced targeted biodistribution and therapeutic efficacy in oncology, ischemic stroke, and chronic inflammatory conditions.

Cite This Study

Zhou et al. (2025) studied this question.

synapsesocial.com/papers/6a7df414cf7e8b32dacb5a4a https://doi.org/10.1016/j.mtbio.2025.101922

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