Ethnic Differences in C-Reactive Protein Concentrations
Why the study?
Are there ethnic differences in C-reactive protein (CRP) concentrations among pre- and perimenopausal women without known CVD?
Population
3154 pre- and perimenopausal women without known CVD and not receiving hormone therapy, mean age 46.2 years…
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
Ethnic CRP differences in women should not yet alter risk models; leaves open mechanisms and prognostic value beyond BMI.
Structured PICO
Are there ethnic differences in C-reactive protein (CRP) concentrations among pre- and perimenopausal women without known CVD?
P
Population
3154 pre- and perimenopausal women without known CVD and not receiving hormone therapy, mean age 46.2 years, multiethnic (47.4% white, 27.7% African-American, 8.5% Hispanic, 7.7% Chinese, 8.6% Japanese).
O
Outcome
C-reactive protein (CRP) concentrationssurrogate
Significant ethnic variations exist in CRP concentrations among women, which are largely but not entirely explained by modifiable risk factors like BMI.
Cite This Study
Kelley-Hedgepeth et al. (2008) studied this question.